A prospective study assessing the impact of Tixel treatment of peri-orbital wrinkles on dry eye symptoms and signs in patients with dry eye:
Volunteers are needed for a study to investigate if a treatment that is currently used to treat wrinkles around the eyes is useful in treating dry eye. To be eligible to participate you: must be at least 18 years of age; have wrinkles around your eyes; have been diagnosed as having dry eye; and not have any eye disease affecting the front of your eyes. The study involves five visits over a period of 18 weeks. You would have your wrinkles treated and an assessment of dry eye. To find out more about the study and to see if you would be eligible to participate please contact: Ms Bhagyashree Rajesh Rawal on 210322284@aston.ac.uk or Dr Raquel Gil-Cazorla on ”r.gil-cazorla@aston.ac.uk
Red / Blue Light Low-Level Light Therapy (REBEL) Study – UK Based
Researchers from Aston Optometry School are assessing how low-level light therapy (LLLT) with different coloured wavelengths (red and blue) work to improve the health of oil glands in the eyelids and treat dry eye disease AND blepharitis. We are seeking adult volunteer participants aged 18 and over who have ALL 3 of the following conditions:
- Dry eye disease
- Oil glands in your eyelids not working properly (called Meibomian gland dysfunction)
- Demodex blepharitis around eyelashes
We will need to check that you are fully suitable and eligible for this study at the first visit.
You will need to attend a total of 4 visits over 8 weeks, each visit lasting about an hour. You will also receive a total of £80 at the end of the 4th visit if you successfully attend all 4 visits. You will be randomised to either the group receiving the red only, blue only, a combination of both red and blue wavelength LLLT treatment, or a sham treatment group. Standard clinical tests will be done at the first, third and fourth visits.
You will not be able to participate if you are pregnant, wore contact lenses in the past 2 weeks or will be during the study, had ocular light therapies in the past 1 month, or had a history of ocular surgery or corneal infections in the past 6 months.
Mechanism of Light-based Therapy (MOLT) Study – UK Based
Researchers from Aston Optometry School are assessing how light-based therapies, known to be effective for dry eye disease treatment, work to improve the health of the oil glands in our eyelids. These include intense pulsed light therapy (IPL) and low-level light therapy (LLLT). We are seeking adult volunteer participants aged 18 and over who are suffering from a specific form of dry eye disease where the oil glands in your eyelids are not working properly (called Meibomian Gland Disease).
You will need to attend a total of 6 visits (4 treatment visits provided for free, 2 to 3 weeks apart, and then 2 follow-up visits 2 weeks and 3 months after the final treatment visit). If you are eligible and suitable for treatment, one of your eyes will be randomised to receiving both IPL and LLLT, and the other eye will receive LLLT alone so that we can compare how these treatments work. The blood flow in your eyelids and nerves on the surface of the eyes will also be analysed using sophisticated, non-invasive instruments during the first and follow-up visits. Each visit lasts about 1.5 hours.
You will not be able to participate if you are pregnant, wore contact lenses in the past 2 weeks or will be during the study, have only one functioing eye, have systemic conditions that can cause dry eye disease such as diabetes or Sjögren’s syndrome, contraindicated for IPL treatment (e.g. have photosensitive epilepsy, used photosensitising medication in the past 3 months, have tattoos, implants, electrical or acoustic prosthetics, semi-permanent make-up, pigmented lesions or skin cancers in the treatment area, have pacemakers or have a dark skin tone), had facial or ocular light therapies in the past 6 months, or had a history of ocular surgery or corneal infections.
